Genotropin® somatropin For Injection Official Site Safety Info

Genotropin® somatropin For Injection Official Site Safety Info

Cases of pancreatitis have been reported rarely in children and adults receiving somatropin treatment, with some evidence supporting a greater risk in children compared with adults. Published literature indicates that girls who have Turner syndrome may be at greater risk than other somatropin-treated children. Pancreatitis should be considered in any somatropin–treated patient, especially a child, who develops persistent severe abdominal pain.

  • It is asingle-chain protein that is composed of 191 amino acids with a molecular weight of approximately 22,000Daltons.GH secretion has many direct and indirect effects on the human body.
  • Genotropin is a very high quality HGH product that is popular among HGH users.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Our mission is to support, not replace, the doctor-patient relationship.
  • These children were extremely overweight, had breathing problems, and/or lung infection.

Patients who received any dose of GENOTROPIN showed significant increases in growth during the first 24 months of study, compared with patients who received no treatment (see Table 5). Children receiving 0.48 mg/kg/week demonstrated a significant improvement in height standard deviation score (SDS) compared with children treated with 0.24 mg/kg/week. Both of these doses resulted in a slower but constant increase in growth between Buy Letrozol 2.5 mg USA months 24 to 72 (data not shown). Changes in body composition were also observed in the patients receiving GENOTROPIN (see Table 4). Treatment with GENOTROPIN did not accelerate bone age, compared with patients who received no treatment. The safety and efficacy of GENOTROPIN in the treatment of pediatric patients with Prader-Willi syndrome (PWS) were evaluated in two randomized, open-label, controlled clinical trials.

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Other common somatropin-related adverse reactions include injection site reactions/rashes and lipoatrophy (6.1) and headaches (6.3). The GENOTROPIN 5 and 12 mg cartridges are color-coded to help ensure proper use with the GENOTROPIN Pen delivery device. Your dose and brand of somatropin, and how often you use it will depend on the condition you are treating. Follow all directions on your prescription label and read all medication guides or instruction sheets.

A lower starting dose and smaller dose increments should be considered for older patients [see Dosage and Administration (2.2)]. In patients with diabetes mellitus requiring drug therapy, the dose of insulin and/or oral/injectable agent may require adjustment when somatropin therapy is initiated [see Warnings and Precautions (5.4)]. Table 1 displays the adverse events reported by 5% or more of adult GHD patients in clinical trials after various durations of treatment with GENOTROPIN.